Dr. Yossi Tsfadia

Dr. Yossi Tsfadia is a senior lecturer at the School of Neurobiology, Biochemistry & Biophysics, at Tel Aviv University.  Its main interest is the study of protein-protein interactions.


Dr. Tsfadia uses Molecular Dynamics simulations, NMA, and docking algorithms, to follow the conformation landscape of protein structures in order to reveal the biochemical mechanism at atomic-scale resolution.  Based on the understanding of the mechanism, his research evolves towards drug designing.   Currently, there are several subjects of interest: 

  • The recognition and interaction of SARS CoV 1, MERS, and SARS CoV 2 Corona Viruses with receptors and antibodies.
  • The mechanism of chemotherapeutic drug resistance caused by the transporter MRP1. 
  • Design of peptides and peptidomimetics that can inhibit the Insulin Degrading Enzyme (IDE) for therapeutic applications in Diabetes.



Email: yossit@tauex.tau.ac.il

Web:  https://tsfadialab.wixsite.com/tsfadialab


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