Prof. Joel Hirsch

Broadly speaking, we are interested in the structural biology of cellular signaling. 

 

We have focused on several systems that play key roles in signal transduction. Our goals are to obtain a mechanistic understanding of these molecules; how they interact, transmit and respond to various cues on the most basic level of physics and chemistry; and how this understanding can forge greater progress in comprehending the general biology to which they are pivotal.

 

Currently we are researching four major areas:

  • Calcium signalling, using voltage-dependent calcium channels and protein calcium sensors.
  • Electrical signaling, using voltage-dependent potassium channels.
  • Protein signaling, using G-protein regulation and protein kinases. 
  • Protein homeostasis, using the mitochondrial HSP60-HSP10 protein complexes.

 

Contact:

Email: gepner@tauex.tau.ac.il

 

 

 

Tel Aviv University makes every effort to respect copyright. If you own copyright to the content contained
here and / or the use of such content is in your opinion infringing, Contact us as soon as possible >>